1H-Indole-1-carboxylic acid, 2-borono-5-bromo-, 1,1-dimethylethyl ester
1-N-Boc-5-bromoindole-2-boronic acid
CAS: 475102-13-7
Molecular Formula: C13H15BBrNO4
1H-Indole-1-carboxylic acid, 2-borono-5-bromo-, 1,1-dimethylethyl ester - Names and Identifiers
1H-Indole-1-carboxylic acid, 2-borono-5-bromo-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C13H15BBrNO4 |
| Molar Mass | 339.98 |
| Density | 1.45 |
| Melting Point | 93 °C |
| Boling Point | 488.3°C at 760 mmHg |
| Flash Point | 249.1°C |
| Vapor Presure | 2.39E-10mmHg at 25°C |
| Appearance | Solid |
| Storage Condition | Keep Cold |
| Refractive Index | 1.576 |
| MDL | MFCD03701683 |
1H-Indole-1-carboxylic acid, 2-borono-5-bromo-, 1,1-dimethylethyl ester - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29310095 |
| Hazard Note | Irritant |
1H-Indole-1-carboxylic acid, 2-borono-5-bromo-, 1,1-dimethylethyl ester - Introduction
Acid is an organic compound that contains the Boron (boron) and Bromoindole (bromoindole) groups in its chemical structure.
nature, acid is a white to light yellow solid, stable at room temperature. It has low solubility in water and is more suitable for use in organic solvents. The compound can be characterized by nuclear magnetic resonance (NMR) and mass spectrometry (MS).
In terms of use, acid is often used as an important intermediate in organic synthesis reactions. It can participate in SuZ-solid phase reaction, Suzuki-Miyaura coupling reaction, etc., and is used to synthesize compounds with indole and boronic acid functional groups. These compounds have important biological activities in the field of medicine and can be used in pharmaceutical research and drug development.
In terms of preparation, the synthesis of acid usually includes a multi-step reaction. First, brominated indole reacts with boronic acid to form 5-bromoindole-2-boronic acid. Next, by chemical reaction with N-tert-butyloxycarbonyl (N-Boc), the N-Boc group is introduced into the target molecule to obtain the final product P acid.
in terms of safety information, acid specific safety information may lack specific information, so the use should follow the laboratory safety practice. In addition, for the use of any chemical substances, it is recommended that users wear personal protective equipment necessary for the laboratory and operate under appropriate conditions to avoid direct contact with skin, eyes or food. Consult chemical suppliers or relevant safety databases for more detailed safety information when required.
nature, acid is a white to light yellow solid, stable at room temperature. It has low solubility in water and is more suitable for use in organic solvents. The compound can be characterized by nuclear magnetic resonance (NMR) and mass spectrometry (MS).
In terms of use, acid is often used as an important intermediate in organic synthesis reactions. It can participate in SuZ-solid phase reaction, Suzuki-Miyaura coupling reaction, etc., and is used to synthesize compounds with indole and boronic acid functional groups. These compounds have important biological activities in the field of medicine and can be used in pharmaceutical research and drug development.
In terms of preparation, the synthesis of acid usually includes a multi-step reaction. First, brominated indole reacts with boronic acid to form 5-bromoindole-2-boronic acid. Next, by chemical reaction with N-tert-butyloxycarbonyl (N-Boc), the N-Boc group is introduced into the target molecule to obtain the final product P acid.
in terms of safety information, acid specific safety information may lack specific information, so the use should follow the laboratory safety practice. In addition, for the use of any chemical substances, it is recommended that users wear personal protective equipment necessary for the laboratory and operate under appropriate conditions to avoid direct contact with skin, eyes or food. Consult chemical suppliers or relevant safety databases for more detailed safety information when required.
Last Update：2024-04-10 22:30:50
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Product Name: (N-Boc-5-bromo-2-indolyl)boronic acid Visit Supplier Webpage Request for quotation
CAS: 475102-13-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 475102-13-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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